ABSTRACT
Objetivo Describir nuestra experiencia con un protocolo basado en el uso de sevoflurano para la sedación y analgesia durante la infiltración de toxina botulínica tipo A (BoNT-A), en niños con parálisis cerebral (PC), especialmente en términos de seguridad y eficacia. Material y métodos Estudio observacional retrospectivo de pacientes con PC a los que se realizó infiltración con BoNT-A bajo sedación con sevoflurano desde noviembre de 2012 hasta diciembre de 2019. Se revisaron las características demográficas, las características clínicas y funcionales, la efectividad de la sedación, los eventos adversos (EA) y la satisfacción del profesional. Resultados Se realizaron 387 sedaciones en 74 pacientes diagnosticados de PC. La sedación efectiva se logró en el 100% de los procedimientos, facilitando la colaboración durante la infiltración y la satisfacción del profesional. Se notificaron EA en el 6,02% de los procedimientos, siendo los más frecuentes las náuseas y los vómitos (3,88%) y la hipoxemia transitoria (2,07%). No se informaron EA graves. No se encontró asociación entre la incidencia de EA y las variables clínicas, funcionales o el riesgo antes de la anestesia. Conclusiones La sedación con sevoflurano muestra resultados prometedores en términos de seguridad y efectividad para el manejo de la agitación y el dolor durante la infiltración de BoNT-A en nuestra práctica clínica diaria. Además, puede facilitar la infiltración, permitir la exploración bajo sedación e infiltración multinivel con buena tolerancia (AU)
Objective This study aimed to describe our experience with a protocol based on sevoflurane sedation to control pain and agitation during botulinum toxin-A (BoNT-A) infiltration in children with cerebral palsy (CP), especially in terms of safety and efficacy. Material and methods We conducted a retrospective observational study of patients diagnosed with CP who underwent BoNT-A infiltration with sevoflurane sedation from November 2012 to December 2019. Demographic, clinical and functional characteristics, the effectiveness of sedation, adverse events (AE) and professional satisfaction were reviewed. Results A total of 387 sedations were successfully performed in 74 patients. Effective sedation was achieved in 100% of procedures, facilitating collaboration during infiltration and improving professional satisfaction. AE were reported in 6.02% of the procedures, the most frequent being nausea and vomiting (3.88%) and transient hypoxemia (2.07%). There were no severe AE. No association was found between the incidence of AE and the clinical and functional variables or risk before anaesthesia. Conclusion Sevoflurane sedation shows promising results in terms of safety and effectiveness for the management of agitation and pain during BoNT-A infiltration in our daily clinical practice. In addition, it can facilitate infiltration, allowing examination under sedation and multilevel infiltration with good tolerance (AU)
Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Botulinum Toxins, Type A/therapeutic use , Cerebral Palsy/drug therapy , Sevoflurane/therapeutic use , Anesthesia/methods , Retrospective Studies , Clinical ProtocolsABSTRACT
OBJECTIVE: This study aimed to describe our experience with a protocol based on sevoflurane sedation to control pain and agitation during botulinum toxin-A (BoNT-A) infiltration in children with cerebral palsy (CP), especially in terms of safety and efficacy. MATERIAL AND METHODS: We conducted a retrospective observational study of patients diagnosed with CP who underwent BoNT-A infiltration with sevoflurane sedation from November 2012 to December 2019. Demographic, clinical and functional characteristics, the effectiveness of sedation, adverse events (AE) and professional satisfaction were reviewed. RESULTS: A total of 387 sedations were successfully performed in 74 patients. Effective sedation was achieved in 100% of procedures, facilitating collaboration during infiltration and improving professional satisfaction. AE were reported in 6.02% of the procedures, the most frequent being nausea and vomiting (3.88%) and transient hypoxemia (2.07%). There were no severe AE. No association was found between the incidence of AE and the clinical and functional variables or risk before anaesthesia. CONCLUSION: Sevoflurane sedation shows promising results in terms of safety and effectiveness for the management of agitation and pain during BoNT-A infiltration in our daily clinical practice. In addition, it can facilitate infiltration, allowing examination under sedation and multilevel infiltration with good tolerance.
Subject(s)
Anesthesia , Botulinum Toxins, Type A , Cerebral Palsy , Neuromuscular Agents , Cerebral Palsy/drug therapy , Child , Humans , Neuromuscular Agents/adverse effects , Observational Studies as Topic , Sevoflurane , Treatment OutcomeABSTRACT
Introducción. El equinismo, que es la deformidad más frecuente en los pacientes con parálisis cerebral, aumenta la inestabilidad, dificulta la marcha y la adaptación a la silla de ruedas. La corrección del equinismo beneficia al niño deambulador, facilita la adecuada colocación del pie en el reposapiés de la silla de ruedas y la posibilidad de usar un calzado convencional en el niño que no tiene capacidad de marcha. El objetivo de este estudio es valorar si el uso nocturno de ortesis de tobillo-pie en ortoposición permite prevenir o diferir la aparición de equinismo y así evitar o retrasar la cirugía de alargamiento tendinoso. Material y método. Se ha realizado un estudio observacional descriptivo retrospectivo, revisando el historial clínico de pacientes diagnosticados de parálisis cerebral, tratados mediante ortesis de tobillo-pie nocturnas en la Unidad de Rehabilitación Infantil del Hospital Virgen Macarena. Resultados. De los 90 pacientes tratados con la ortesis de tobillo-pie nocturna, el 88,9% consiguió el rango de flexión dorsal necesario para la deambulación (≥ 10°) o la correcta adaptación a la silla de ruedas y al calzado (≥ 0°). Únicamente en 9 pacientes (10% de los casos) no se alcanzaron los objetivos pretendidos. Conclusión. El tratamiento preventivo con ortesis rígidas constituye una opción de primera línea en el tratamiento de la parálisis cerebral. El uso reglado y mantenido de las ortesis de tobillo-pie nocturnas puede retrasar la aparición del equinismo en la parálisis cerebral y permite diferir o evitar la cirugía con un beneficio funcional evidente (AU)
Introduction. Equinus, the most common deformity in patients with cerebral palsy, increases instability and impairs gait and adaptation to a wheelchair. Correction of equinus benefits walking children and aids proper placement of the foot on the footrest of a wheelchair. It also allows the possibility of using conventional footwear in children with no ability to walk. The aim of this study was to assess whether the use of an ankle-foot orthosis at night, keeping the foot in orthoposition, can prevent or delay the onset of equinus and thus prevent or delay tendon lengthening surgery. Material and methods. We performed a retrospective observational study based on a chart review of 90 patients diagnosed with cerebral palsy treated with a nocturnal ankle-foot orthosis in the Children's Rehabilitation Unit at Hospital Virgen Macarena in Spain. Results. Of the 90 patients treated with nocturnal ankle-foot orthosis, 88.9% achieved the dorsiflexion necessary for ambulation (≥ 10°) or adequate adaptation to a wheelchair and footwear (≥ 0°). Only 9 patients (10%) did not achieve the intended objectives with the use of the splint. Conclusion. Preventive treatment with a rigid ankle-foot orthosis is a widely accepted practice that constitutes a first-line option in the treatment of cerebral palsy. Systematic and persistent use of a nocturnal ankle-foot orthosis can delay the onset of equinus in cerebral palsy and can delay or avoid surgery, with a clear functional benefit (AU)
Subject(s)
Female , Humans , Male , Foot Orthoses/trends , Foot Orthoses , Equinus Deformity/prevention & control , Equinus Deformity/rehabilitation , Cerebral Palsy/complications , Cerebral Palsy/rehabilitation , Retrospective Studies , Somnambulism/complications , Somnambulism/rehabilitation , Equinus Deformity/physiopathology , Equinus Deformity/surgery , Equinus DeformityABSTRACT
El síndrome de Costello (SC) es una enfermedad poco frecuente, caracterizada por talla baja, retraso en el desarrollo y facies característica. Los problemas ortopédicos son una parte significativa para esta población. Se presenta el caso de un paciente con un SC y deformidad del raquis asociada (AU)
Costello syndrome (CS) is an uncommon disease characterized by short stature, delayed development and typical facies. The orthopedic problems account for a significant part for this population. We present the case of a patient with CS and associated spine deformity (AU)
